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PI3K inhibitor LY294002, on the other hand, reversed this effect of puerarin. Puerarin alleviates migration of mesenchymal-like cells by decreasing MMPs’ protein expression. Puerarin has protective results on H2O2-induced HCAECs EndMT by lowering oxidative worry, activating the PI3K/Akt pathway, and limiting cell migration. Puerarin has a protect

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